ABSTRACT
Introduction: Accurate diagnosis of the COVID-19 disease is important. Currently, chest computed tomography (CT) and reverse polymerase chain reaction (RT-PCR) are being used for the diagnosis of the COVID-19 disease. This study was performed to evaluate the Chest computed tomography (CT) diagnostic value in comparison with the RT-PCR method among COVID-19 patients. Methods: This cross-sectional study was performed on suspected cases of COVID-19 in Imam Khomeini Hospital, Jiroft, Iran. Studied patients were evaluated via both a chest CT scan and nasopharyngeal swab for SARS-CoV-2 detection. Data was collected using a self-administered checklist, including demographic information, medical history, and symptoms of COVID-19, chest CT scan, and RT-PCR findings. Data were analyzed using SPSS-V21. Results: One thousand and ninety (1090) cases participated in the study;the mean age of the cases of COVID-19 was 48.20± 7.31 years old. The results of the RT-PCR test were 410 (37.6%) positive and 680 (62.4%) negative cases. According to the results of RT-PCR, which is the gold standard method, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive values of chest CT were 98.5%. (99.4-96.8 CI: 95%), 55.7% (59.5 – 51.9 CI: 95%), 71.5% (74.4-69.0 CI: 95%), 57.3% (60.9 – 53.5 CI: 95%), and 98.4% (99.4%-99.6 CI: 95%), respectively. Discussion: The results of the present study showed that a chest CT scan is highly sensitive for the diagnosis of the COVID-19 disease. Therefore, it can be used as a suitable method for screening and early detection, which requires knowledge of its common radiologic patterns. However, the results showed that the use of this method has low specificity, so it cannot be used for definitive diagnosis and should be used as a complementary method concomitant to the RT-PCR test. © 2022 Razzaghi et al.
ABSTRACT
OBJECTIVE: We compared demographic and clinic-pathological variables related to the number of surgeries for thyroid conditions or for cancer, morbidity, and fine needle aspiration (FNA) practices among Covid19 pandemic phases I, II, III and the same seasonal periods in 2019. METHODS: The prospective database of the Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Changchun, China was used for this study. Covid19 emergency levels were stratified according to the World Health Organization: phase I (January 25-February 25, 2020), phase II (February 26-March 19), phase III (March 20-April 20). RESULTS: There were fewer outpatient FNAs and surgeries in 2020 than in 2019. There were no thyroid surgeries during phase I. There were also fewer surgeries for cancer with a significant reduction of advanced stage cancer treatments, mainly stage T1b N1a in phase II and T3bN1b in phase III. Operative times and postoperative stays were significantly shorter during the pandemic compared to our institutional baseline. In phase III, vocal cord paralysis (VCP) increased to 4.3% of our baseline numbers (P = 0.001). There were no cases of Covid19-related complications during the perioperative period. No patients required re-admission to the hospital. CONCLUSION: The Covid19 outbreak reduced thyroid surgery patient volumes. The decrease of Covid19 emergency plans contributed to unexpected outcomes (reduction of early stage cancer treatment, decreased operative times and hospital stays, increased VCP rate).